December 2003
November 2003
October 2003
September 2003
August 2003
July 2003
June 2003
May 2003
May 2003 Mass Spectrometry Supplement
April 2003
March 2003
February 2003
January 2003
2002
2001
2000
1999
1998
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1995-1996
December 2003, Volume 18, Number 12
CORPORATE CAPABILITIES
ARTICLE
- Test of an In Vivo Method to Detect Chloroplast Division in Crop Plants, Part III: Statistical Proofs of Observation and General Utility of the Method
Ping Zheng, Karim Ammar, Anne-Marie Michelle Girard, Steve Rodermel, David R. Thomas, Li Ning, James B. Callis, Gerry E. Edwards, Larry Daley
This article is the third installment in a series about a novel spectrofluorometric method that allow for in vivo observation of the division of chlorplast populations in leaves of Arabidopsis thalania.
COLUMNS
- Chemometrics: Derivatives in Spectroscopy, Part III: Computing the Derivative
Howard Mark, Jerome Workman, Jr.
This series about derivatives in spectroscopy continues with a discussion about some of the practical aspects of computing the derivative.
- Limits of Detection in Spectroscopy
Volker Thomsen, Debbie Schatzlein, David Mercuro
A diagrammatic view of the concept of detection limits is presented that effectively shows its relationship to the reproducibility of measurements on the blank.
DEPARTMENTS
RESOURCE SECTION
- Call for Papers
- Editorial Index
- Information for Authors
- Directory of Associations
November 2003, Volume 18, Number 11
ARTICLES
- Processing Techniques for Handling Multiple Spectra
David L. Wooton
The author discusses several mathematical processing methods for
handling, assessing, and studying groups containing multiple spectra.
The processing techniques feature standard mathematical tools that are
used to study a series of numerical results.
- Temperature-Induced Effect on Surface-Enhanced Raman Scattering of p,m-Hydroxybenzoic Acid on Silver Nanoparticles
Lili Xu and Yan Fang
This article examines temperature-induced effects on surface-enhanced Raman scattering of PHBA and MHBA adsorbed on silver colloidal particles.
COLUMNS
- Molecular Spectroscopy Workbench
Near-Infrared Spectroscopy as a Process Analytical Tool, Part I: Laboratory Applications
Katherine A. Bakeev
Rapid near-infrared spectroscopy measurement near the process line of lab applications may speed up the process.
- The Baseline Photoelectron Spectroscopy
David W. Ball
The author discusses photoelectron spectroscopy theory and describes radiation sources used in the technique.
DEPARTMENTS
- News Spectrum
- Resources
- Calendar
- Advertisers
- End of the Spectrum
October 2003, Volume 18, Number 10
ARTICLES
- Rays of Hope: Spectroscopy as an Emerging Tool for Cancer Diagnostics and Monitoring
Michael MacRae
Vibrational and fluorescence spectroscopy, laser light-scattering techniques, and other optics-based approaches are gaining momentum in the quest for early detection and more effective treatment of cancer.
- Tech Note
High-Resolution Ultrasonic Spectroscopy for Analysis of Chemical Reactions in Real Time
E. Kudryashov, C. Smyth, B. O'Driscoll, and V. Buckin
This article discusses direct real-time monitoring of chemical reactions, an important tool in industrial processes in industries such as chemical, biotechnology, food, and pharmaceutical.
COLUMN
- Molecular Spectroscopy Workbench
A Comparison between Validating Laboratory and Process Near-Infrared Spectrophotometers
Gary E. Ritchie
The author describes applying validation principles originally designed
for lab instruments to process instruments.
DEPARTMENTS
- News Spectrum
- Resources
- Advertisers
September 2003, Volume 18, Number 9
ARTICLES
- Pharmaceutical Industry Embraces NIR Technology
Hallie Forcinio
The author discusses the use of near-infrared (NIR) spectroscopy to check incoming drug substances, excipients, and packaging materials in warehouse settings, and how the technology is used on the production floor to monitor characteristics such as blend uniformity, moisture content, and dissolution rate.
- Molecular Spectroscopy Workbench
The Process Analytical Technologies Initiative:
What Is It, and Where Does Spectroscopy Come In?
Emil W. Ciurczak
The challenges for the spectroscopy industry regarding the process analytical technologies initiative are immense, but so are the potential payoffs.
- Atomic Spectroscopy Perspectives
A Preview of the 2004 Winter Conference on Plasma Spectrochemistry
D. Conrad Grégoire
See what's in store for the 13th biennial Winter Plasma Spectrochemistry Conference, slated for January 2-8, 2004 in Fort Lauderdale, Florida.
- Chemometrics
Derivatives in Spectroscopy: Part II - The True Derivative
Howard Mark and Jerome Workman Jr.
The authors continue their examination of derivatives, including some discussion about their observations concerning the change in magnitude of the compound values of the derivatives as the wavelength spacing over which they are computed is changed.
DEPARTMENTS
- News Spectrum
- Resources
- Calendar
- Advertisers
- End of Spectrum
August 2003, Volume 18, Number 8
BUYERS' GUIDE
- SPECTROSCOPIC INSTRUMENTATION/SPECTROMETER SYSTEMS
- OPTICS, ELECTRO-OPTICS, FIBER OPTICS, AND RELATED COMPONENTS
- SAMPLING/SAMPLE HANDLING
- SPECTROSCOPY SOFTWARE/HARDWARE/AUTOMATION PRODUCTS
- SPECTROSCOPY SERVICES
- GENERAL SCIENTIFIC EQUIPMENT AND ACCESSORIES
- PROCESS ANALYTICAL INSTRUMENTS
- BIOANALYSIS INSTRUMENTS
DEPARTMENTS
- FROM THE EDITOR
- PRODUCT INDEX
- MANUFACTURER DIRECTORY
- WEB SHOWCASE
July 2003, Volume 18, Number 7
ARTICLES
- An Overview of New Products at the Denver X-ray Conference
Michelle Nicolson, Joseph Perry, and Sarah K. Thompson
A brief overview of some of the latest spectroscopy-related equipment and supplies scheduled to be introduced at the 2003 Denver X-ray Conference at the Denver Marriott Tech Center Hotel in Denver, Colorado, August 4-8, 2003.
- The X-ray Spectrum of Monazite
Volker Thomsen and Debbie Schatzlein
The x-ray energy spectrum provides rapid identification of mineral samples.
COLUMN
- Focus on Quality
Validation of Spectrometry Software: Part VI - Designing Performance Qualification Tests
R.D. McDowall
The author discusses how to identify some of the performance qualification tests to apply to spectrometry software, how to write the test procedures and instructions, and how to execute the actual testing.
DEPARTMENTS
- News Spectrum
- Resources
- Calendar
- Advertisers
- End of Spectrum
June 2003, Volume 18, Number 6
ARTICLES
- ADME/Tox Profiling
Using Coulometric Electrochemistry and Electrospray Ionization Mass Spectrometry
Paul Gamache, Ray Smith, Ryan McCarthy, John Waraska, and Ian Acworth
The authors discuss the use of serial coulometric flow cells coupled online with electrospray ionization mass spectrometry in predictive assays for absorption, distribution, metabolism, excretion, toxicity (ADME/Tox), and stability implemented at early stages of drug discovery.
- Challenges in the Interpretation of Data from Hyphenated Techniques
Part I: General Principles
Paul N. Bourassa
This first installment in a series about challenges and pitfalls in interpreting data from hyphenated techniques explores general concepts in initial approaches.
- Tech Note:
Improving Ionization in Mass Spectrometry
Ronald Starcher
The author discusses an alternative to filament sources when working with electron ionization.
DEPARTMENTS
- News Spectrum
- Products Guide
- Advertisers
- End of Spectrum
May 2003, Volume 18, Number 5
FEATURE
- Pittcon 2003 Review
The 18th Annual Wrap-up of New Spectroscopy Instrumentation Introduced at the Pittsburgh Conference
Michelle Nicolson, Joseph Perry, and Sarah K. Thompson
Spectroscopy's annual overview presents new instrumentation that was
introduced at the Pittsburgh Conference and Exposition on Analytical
Chemistry and Applied Spectroscopy (PittCon), held this year March 10 - 13
in Orlando.
ARTICLE
- Identification of Unanticipated Compounds by High-Resolution Mass Spectrometry
Andrew H. Grange and G. Wayne Sovocool
Often, mass spectra of compounds found in water supplies are not found
in water supplies are not found in mass spectral libraries. Ion compound
elucidation (ICE) provides the elemental compositions of the ions
observed in their mass spectra. This information is used to identify the
compounds.
COLUMN
- Mass Spectrometry Forum: Part III - More Mass Spectrometry/Mass Spectrometry
Kenneth L. Busch
The third installment in a four-part series on chemical noise in mass
spectrometry.
DEPARTMENTS
May 2003 Mass Spectrometry Supplement, Volume 18, Number 5
FEATURE
- What's New in Mass Spectrometry
The staffs of Spectroscopy and LCGC North America present information
about some of the latest mass spectrometry instruments, accessories, and
supplies.
ARTICLES
- Comparison of Quadrupole, Time-of-Flight, and Fourier Transform Mass Analyzers for LC-MS Applications
Bernard K. Choi, David M. Hercules, Tianlan Zhang, and Arkady I. Gusev
The authors investigated the analytical capabilities of three types of mass analyzers for liquid chromatography electrospray mass spectrometry (LC-MS) applications, studying instrument parameters and issues related to sample preparation on the performance of LC-MS analytical methods.
- Units in Mass Spectrometry
Kenneth L. Busch
This article focuses on units in mass spectrometry, with commentary on
history, usage, and debate.
DEPARTMENTS
- Bookshelf
- Resources
- Calendar
- Web Showcase
- From the Publishers
- Advertisers
April 2003, Volume 18, Number 4
ARTICLES
- Development of an In Situ Spectroscopic Method for Cleaning Validation Using Mid-IR Fiber Optics
Narinder K. Mehta, Javier Goenaga-Polo, Samuel P. Hernández-Rivera,
David Hern ndez, Mary A. Thomson, and Peter J. Melling
This article describes the use of a spectroscopy probe combined with a
grazing-angle reflectance sampling head, which can be used to validate
cleanliness with improved accuracy.
- An Overview of New Products at Photonics West
This article provides a brief overview of some of the latest spectroscopy-related equipment and supplies that were shown at the 2003 Photonics West conference at the San Jose Convention Center, San Jose, CA, January 25 - 31, 2003.
COLUMNS
- Focus on Quality: Validation of Spectrometry Software, Part V - Performance Qualification
R.D. McDowall
This installment of the ongoing series discusses performance qualification of software in regard to system requirements.
- Chemometrics: Derivatives in Spectroscopy, Part I - The Behavior of the Derivative
Howard Mark and Jerome Workman Jr.
The authors begin a new series of columns about derivatives of spectra.
DEPARTMENTS
- News Spectrum
- Resources
- Calendar
- Advertisers
- End of Spectrum
March 2003, Volume 18, Number 3
SPOTLIGHT
- The 2003 Spectroscopy Survey of Salaries and Employment Issues
Most spectroscopists who responded to our annual survey are satisfied with their current position, while keeping a positive outlook toward the future.
Industry Trends
- Global Economic Upturn in 2003 Bodes Well for Spectroscopy Market
Showcase
- Products for Spectroscopy
Special Section: Space Research
- 2003 - The Year of Mars
- Uncovering the Secret of the Rocks with LIBS
- The Planetary Shared Sample Library - A New Tool for Planetary Science
DEPARTMENTS
- From the Editor
- News Spectrum
- Book Review
- Web Showcase
- Advertisers
- Calendar
February 2003, Volume 18, Number 2
ARTICLES
- Unilateral Nuclear Magnetic Resonance for Quality Control: The NMR-MOUSE
B. Blümich, S. Anferova, K. Kremer, S. Sharma, V. Herrmann, and A. Segre
The authors discuss the principles of unilateral nuclear magnetic resonance with applications to elastomers and nondestructive in situ inspection of a wet fresco from ancient Rome.
- Tech Note: FT-IR and Raman Microscopy on a United Platform - A Technology Whose Time Has Come
Fran Adar, Gwenaelle leBourdon, John Reffner, and Andrew Whitley
This article reviews the history and discusses the advantages and disadvantages of FT-IR and Raman microscopes. The authors describe new instrumentation that incorporates both techniques on one platform.
COLUMNS
- Tutorial: Beginner's Guide to ICP-MS, Part XIV - Sampling Accessories, Part II
Robert Thomas
- Mass Spectrometry Forum: Chemical Noise in Mass Spectrometry, Part II - Effects of Choices in Ionization Methods on Chemical Noise
Kenneth L. Busch
- Focus on Quality: Validation of Spectrometry Software, Part IV - Qualification of the Software and System
R.D. McDowall
- The Baseline: M”ssbauer Spectroscopy
David W. Ball
DEPARTMENTS
- News Spectrum
- PittCon Showcase
- Calendar
- Advertisers
- End of Spectrum
APPLICATION NOTEBOOK SUPPLEMENT
Molecular Spectroscopy
- Qualitative Analysis of Powders in Amber Colored Vials
by use of NIR Technology
Analytical Spectral Devices
- Analysis of Salts in Aqueous Solutions by NIR
Ronald Rubinovitz, Buchi Analytical, Inc.
- Using FTIR with Packaging Materials
Mark Druy, Digilab, LLC
- Thin Film Analysis by Grazing Angle ATR Spectroscopy
M. Milosevic and S.L. Berets, Harrick Scientific Corporation
- Raman Multiwell Analyzer:
High Throughput Screening Spectroscopy
Jobin Yvon
- In Situ Crystallization Monitoring
Kaiser Optical Systems, Inc.
- Light-Guiding Fused-Silica Capillary Tubing
Joe Macomber and Gary Nelson, Polymicro Technologies, LLC
- Renishaw's SEM-Raman System
Renishaw Inc
- Infrared Microanalysis of Pharmaceutical Polymorphic Forms
with the IlluminatIR™
SensIR Technologies
- Potassium Dichromate for Validation of Spectrophotometer
UV Absorbance Scale
John Webster, Starna Cells, Inc.
- Determination of Unsulfonated
Matter in Linear Alkyl Benzene
Sulfonic Acids Using
an InfraCal IR Filtometer
Wilks Enterprise, Inc.
Atomic Spectroscopy
- Portable XRF System in Art and Archaeology
Thanos Pantazis, Amptek Inc.
- S2 RANGER EDXRF Analysis of Blast Furnace Slags
Kai Behrens, Bruker AXS GmbH
- Direct Elemental Analyses of Ink on Paper by Laser Ablation
ICP-MS
Alan Koenig, CETAC Technologies
- Reporting Statistical Uncertainty of Certified Values for
Reference Materials
Ralph H. Obenauf and Nimi Kocherlakota, SPEX CertiPrep
- Innovative New High-Sensitivity, 90-Degree Reflecting
ICP-MS Ion Optics for Routine Sample Analysis
Shane Elliott, Iouri Kalinitchenko, Thorsten Hoss*; Varian Australia
Pty. Ltd.; *Varian Deutschland GmbH
Mass Spectrometry
- Representation of Chemical Structures from Partial to Final
Structure - Accelerating Mass Spectrometric Interpretation
Michael Hachey and Mark Bayliss, Advanced Chemistry
Development
- Improving the Operation of Your Mass Spectrometer
Ron Starcher, Ph.D., BURLE Electro-Optics, Inc.
DEPARTMENTS
- From the Publishers
- Web Showcase
- Spectroscopy Market Profiles
- Call for Application Notes
January 2003, Volume 18, Number 1
ARTICLES
- The Benefits of Dynamic Reaction Cell ICP-MS Technology to Determine Ultratrace Metal Contamination Levels in High-Purity Phosphoric and Sulfuric Acid
Katsu Kawabata, Yoko Kishi, and Robert Thomas
This article discusses the applicability of a quadrupole-based
ICP-MS fitted with a dynamic reaction cell to analyze high-purity
phosphoric and sulfuric acid used in the semiconductor industry.
- Unique Atomic Spectroscopy Aims at Answering a Universal Question
Richard Gaughan
By spectroscopically analyzing atoms created when antiprotons collide with
helium, physicists at CERN are measuring the properties of antimatter with
unprecedented accuracy.
COLUMN
- Chemometrics: Analysis of Noise, Part XIV
Howard Mark and Jerome Workman Jr.
DEPARTMENTS
- News Spectrum
- Resources
- Web Watch
- Calendar
- Advertisers